Chapter 6.  Ion Channels

  1. Which of the following is a true statement:

    2. a. Ion channels are glycoproteins
    b. The action potential involves channels permeable to the sodium chloride molecule
    c. Ion channels require active transport
    d. All of the above are true
  2. Malfunction of ion channels is not important in:

    3. a. Hyperkalemic periodic paralysis
    b. Myasthenia gravis
    c. Batten's disease
    d. Fugu poisoning
  3. Ion channel "gating" refers to:

    4. a. The way in which the ion channel protein is folded
    b. The way in which the channel is activated
    c. Patch clamp recording
    d. Slope conductance
  4. Ion channel selectivity is related to (pick one):

    5. a. Ionic radius
    b. An ion's waters of hydration
    c. Charged particles lining the channel
    d. All of the above
  5. Which of the following are characteristics of potassium channels:

    6. a. They cause depolarization from resting membrane potential
    b. They are found only in neurons
    c. They cause membrane hyperpolarization
    d. They account for the initial upstroke of the action potential

Chapter 7.  Membrane Potential

  1. Non-gated channels account for the resting membrane potential

    2. a. True
    b. False
  2. Which ions are important in setting neuronal resting membrane potential:

    3. a. sodium
    b. potassium
    c. calcium
    d. A and B
    e. All of the above
  3. Glial cells at rest are permeable only to potassium, so (choose one)

    4. a. It will require less energy to maintain their resting membrane potential than for neurons
    b. They will have small action potentials
    c. The reversal potential for potassium will approach that for sodium ions
    d. The cells will achieve electroneutrality
  4. The Goldman equation is (choose one):

    5. a. Necessary to calculate electrochemical driving force
    b. A way to calculate resting membrane potential in terms of ionic permeabilities
    c. Contains permeability factors for calcium, magnesium, chloride, sodium, and potassium
  5. Ohm's law is:

    6. a. E = I * R
    b. I = E * g
    c. Both A and B
    d. None of the above


This is a take-home test due 10/2/01
A score of 80% or better is required.